Summary[edit] Description: English: Intermediate magnification micrograph of colonic pseudomembranes in Clostridium difficilecolitis, less precisely also known as pseudomembranous colitis. Colonic resection. H&E stain. The presence of pseudomembranes is not synonymous with Clostridium difficile colitis; pseudomembranes may arise due to other infectious organisms and/or bowel ischemia. As the name implies, pseudomembranes are not real membranes; they represent necrotic debris that is attached to the colonic wall and may vaguely resemble a volcanic eruption, when examined microscopically. Related images Low mag. Intermed. mag. Date:. Source: Own work. Author: Nephron.